{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Chad Deisenroth", "hasEmail": "mailto:deisenroth.chad@epa.gov"}, "description": "Dataset for 'Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening', Garnovskaya, et al., Toxicology in Vitro, Vol 92, 105659, Oct 2023, https://doi.org/10.1016/j.tiv.2023.105659. Contains the ToxCast Pipeline datasets and curve fits that can be pulled up from InvitroDB on the CompTox Chemicals Dashboard. \n\nThis dataset is associated with the following publication:\nGarnovskaya, M., M. Feshuk, W. Stewart, K. Friedman, R. Thomas, and C. Deisenroth. Evaluation of a High-throughput H295R Homogenous Time Resolved Fluorescence Assay for Androgen and Estrogen Steroidogenesis Screening.   TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 92: 105659, (2023).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1530103/ccte_deisenroth_htrf_08AUG2022.pdf", "mediaType": "application/pdf", "title": "ccte_deisenroth_htrf_08AUG2022.pdf"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1530103/ccte_deisenroth_htrf_08AUG2022.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "ccte_deisenroth_htrf_08AUG2022.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1530103/ccte_deisenroth_htrf_fsk_08AUG2022.pdf", "mediaType": "application/pdf", "title": "ccte_deisenroth_htrf_fsk_08AUG2022.pdf"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1530103/ccte_deisenroth_htrf_fsk_08AUG2022.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "ccte_deisenroth_htrf_fsk_08AUG2022.xlsx"}], "identifier": "https://doi.org/10.23719/1530103", "keyword": ["High throughput screening", "New Approach Methods (Alternatives to Animal Testing)", "androgen", "endocrine toxicology", "estrogen", "steroidogenesis"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2022-08-08", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1016/j.tiv.2023.105659"], "rights": null, "title": "Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening"}