{"@type": "dcat:Dataset", "accessLevel": "public", "bureauCode": ["009:25"], "contactPoint": {"@type": "vcard:Contact", "fn": "NIH", "hasEmail": "mailto:info@nih.gov"}, "description": "Inherited susceptibility to rheumatoid arthritis (RA) is associated\t\t\t with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1\t\t\t molecules. Transgenic mice expressing these major histocompatibility complex\t\t\t (MHC) class II molecules have been developed to generate humanized models for\t\t\t RA. The relevance of these models for understanding RA will be discussed.", "distribution": [{"@type": "dcat:Distribution", "description": "Visit the original government dataset for complete information, documentation, and data access.", "downloadURL": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130004/", "mediaType": "text/html", "title": "Official Government Data Source"}], "identifier": "https://healthdata.gov/api/views/ie28-y5zg", "issued": "2025-07-14", "keyword": ["genetic-susceptibility", "hla-dr4", "nih", "rheumatoid-arthritis", "transgenic-mouse-model"], "landingPage": "https://healthdata.gov/d/ie28-y5zg", "modified": "2025-09-06", "programCode": ["009:048"], "publisher": {"@type": "org:Organization", "name": "National Institutes of Health"}, "theme": ["NIH"], "title": "Association of MHC and rheumatoid arthritis: HLA-DR4 and rheumatoid  arthritis - studies in mice and men"}