{"@type": "dcat:Dataset", "accessLevel": "public", "bureauCode": ["009:25"], "contactPoint": {"@type": "vcard:Contact", "fn": "NIH/NCBI Data Team", "hasEmail": "mailto:info@ncbi.nlm.nih.gov"}, "description": "(57) A process for the preparation of an aryloxypropanolamine of the formulawherein Ar is a carbocyclic or heterocyclic aromatic group and R is an alkyl or substituted alkyl group having 1 to 6 carbon atoms, characterized in subjecting a compound of the formulato oxidative deavage to a dialdehyde of the formulawhich is then made subject to reduction, amination, acetal hydrolysis, and, where required, removal of a nitrogen protective group, to the formation of a compound of formula I, or an acid accition salt thereof, a compound of formula II and the preparation thereof from mannitol.", "distribution": [{"@type": "dcat:Distribution", "description": "Access the complete Patent AT-E40108-T1: [Translated] PROCESSES FOR THE PREPARATION OF PHARMACEUTICALLY ACTIVE ARYLOXYPROPANOLAMINE COMPOUNDS. on the official website.", "downloadURL": "https://pubchem.ncbi.nlm.nih.gov/patent/AT-E40108-T1", "mediaType": "text/html", "title": "Official Data Source"}], "identifier": "https://healthdata.gov/api/views/q94w-dfiv", "issued": "2025-09-05", "keyword": ["chemistry", "innovation", "patent", "pubchem", "research"], "landingPage": "https://healthdata.gov/d/q94w-dfiv", "modified": "2025-09-06", "programCode": ["009:066"], "publisher": {"@type": "org:Organization", "name": "National Center for Biotechnology Information (NCBI)"}, "theme": ["NIH"], "title": "Patent AT-E40108-T1: [Translated] PROCESSES FOR THE PREPARATION OF PHARMACEUTICALLY ACTIVE ARYLOXYPROPANOLAMINE COMPOUNDS."}