{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Jennifer Olker", "hasEmail": "mailto:olker.jennifer@epa.gov"}, "description": "This excel file contains the resultant data from a study on iodotyrosine deiodinase in the model amphibian species, Xenopus laevis. These data include: tadpole growth and development, thyroid hormones in plasma and glands, and expression of thyroid-relevant genes. The initial worksheet tab that provides metadata for each dataset included in the other worksheets that make up the file. \n\nThis dataset is associated with the following publication:\nOlker, J., J. Haselman, P. Kosian, K. Donnay, J. Korte, C. Blanksma, M. Hornung, and S. Degitz. Evaluating iodide recycling inhibition as a novel molecular initiating event for thyroid axis disruption in amphibians.   TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA,  166(2): 318-331, (2018).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1500003/Olker_et_al_IYD_180803.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Olker_et_al_IYD_180803.xlsx"}], "identifier": "https://doi.org/10.23719/1500003", "keyword": ["Xenopus laevis", "amphibian metamorphosis", "endocrine disruption", "iodine deficiency", "iodotyrosine deiodinase", "thyroid"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2018-08-03", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1093/toxsci/kfy203"], "rights": null, "title": "Iodotyrosine deiodinase: mRNA expression and experimental inhibition study in Xenopus laevis"}