{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "David Herr", "hasEmail": "mailto:herr.david@epa.gov"}, "description": "Characterization of 100 chemicals for electrophillic potential using Hard and Soft Acid and Bases theory. The chemicals were ranked for electrophillic potential and a group of chemicals within a range of electrophillic values were identified as having properties similar to other neurotoxicants. \n\nThis dataset is associated with the following publication:\nMelnikov, F., B. Geohagen, T. Gavin, R. LoPachin, P. Anastas, P. Coish, and D. Herr. Application of the Hard and Soft, Acids and Bases (HSAB) Theory as a Method to Predict Cumulative Neurotoxicity.   NEUROTOXICOLOGY. Elsevier B.V., Amsterdam,  NETHERLANDS, 79: 95-103, (2020).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504235/Melinikov_Gavin_DataFiles_r1.zip", "mediaType": "application/x-zip-compressed", "title": "Melinikov_Gavin_DataFiles_r1.zip"}], "identifier": "https://doi.org/10.23719/1504235", "keyword": ["HSAB", "adducts", "in silico", "neurotoxicity"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2020-04-22", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1016/j.neuro.2020.04.009"], "rights": null, "title": "Melnikov_etal_Hard and Soft Acid and Base Characterization of 100 Chemicals"}