{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Katie Friedman", "hasEmail": "mailto:paul-friedman.katie@epa.gov"}, "description": "This work estimates benchmarks for new approach method (NAM) performance in predicting organ-level effects in repeat dose studies of adult animals based on variability in replicate animal studies. Data for Paul Friedman et al., \u2018Reproducibility of organ-level effects in repeat dose animal studies\u2019, Computational Toxicology, Vol 28, 100287, Nov 2023, https://doi.org/10.1016/j.comtox.2023.100287. \n\nThis dataset is associated with the following publication:\nFriedman, K., M. Foster, L.L. Pham, M. Feshuk, S. Watford, J. Wambaugh, R. Judson, R. Setzer, and R. Thomas. Reproducibility of organ-level effects in repeat dose animal studies.   Computational Toxicology. Elsevier B.V., Amsterdam,  NETHERLANDS, 28: 100287, (2023).", "distribution": [{"accessURL": "https://clowder.edap-cluster.com/datasets/646d247fe4b08a6b394d2853", "title": "https://clowder.edap-cluster.com/datasets/646d247fe4b08a6b394d2853"}, {"accessURL": "https://github.com/USEPA/CompTox-Reproducibility-Organ-Effects", "title": "https://github.com/USEPA/CompTox-Reproducibility-Organ-Effects"}], "identifier": "https://doi.org/10.23719/1529446", "keyword": ["Organ", "Repeat dose", "ToxRefDB", "variability"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2023-05-24", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1016/j.comtox.2023.100287"], "rights": null, "title": "Reproducibility of organ-level effects in repeat dose animal studies"}