{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Daniel Villeneuve", "hasEmail": "mailto:villeneuve.dan@epa.gov"}, "description": "The present study highlights the utility of bioeffects-based monitoring in conjunction with analytical chemical measurements of surface waters on the Colorado River associated with a historically bioactive wastewater treatment plant effluent. Concurrent with chemical monitoring and in vitro bioactivity measurements, in situ caged fish systems were employed to evaluate the potential bioavailability of predicted biologically-active contaminants associated with ER, GR, and PPAR-associated activities. The present study compares the effects of a wastewater treatment plant facility upgrade on bioactive contaminant loading. \n\nThis dataset is associated with the following publication:\nCavallin, J., W. Battaglin, J. Beihoffer, B. Blackwell, P. Bradley, A. Cole, D. Ekman, R. Hofer, J. Kinsey, K. Keteles, D. Winkelman, and D. Villeneuve. Effects-Based Monitoring of Bioactive Chemicals Discharged to the Colorado River Before and After a Municipal Wastewater Treatment Plant Replacement.   ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 55(2): 974-984, (2021).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1519052/Cavallin%20et%20al_Moab%20caged%20fish_Science%20Hub_12-15-2020.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Cavallin et al_Moab caged fish_Science Hub_12-15-2020.xlsx"}], "identifier": "https://doi.org/10.23719/1519052", "keyword": ["adverse outcome pathway", "aquatic ecosystems", "ecotoxicology", "endocrine disruption", "fish", "in vitro bioassays", "screening and prioritization", "wastewater treatment plant"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2020-07-10", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1021/acs.est.0c05269"], "rights": null, "title": "Effects-based monitoring of bioactive contaminants discharged to the Colorado River before and after a municipal wastewater treatment facility replacement"}