{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Ann Richard", "hasEmail": "mailto:richard.ann@epa.gov"}, "description": "The experimental data were taken from Simon et al., who compiled potency data for effects related to neurotoxicity from four experimental datasets, Stenberg et al. [18] and Wigestrand et al. The measures of potency were EC50 (\u00b5M) or IC50 values for all the effects except Stenberg data, which were expressed as a percentage of the control uptake for different concentrations measured. \n\nThis dataset is associated with the following publication:\nPradeep, P., L. Carlson, R. Judson, G. Lehmann, and G. Patlewicz. Integrating data gap filling techniques: A case study predicting TEFs for neurotoxicity TEQs to facilitate the hazard assessment of polychlorinated biphenyls.   REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, USA, 101: 12-23, (2019).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1503181/Figures_code.zip", "mediaType": "application/x-zip-compressed", "title": "Figures_code.zip"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1503181/NEQ-allAssays.csv", "mediaType": "application/vnd.ms-excel", "title": "NEQ-allAssays.csv"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1503181/NEQ.csv", "mediaType": "application/vnd.ms-excel", "title": "NEQ.csv"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1503181/PCBs.csv", "mediaType": "application/vnd.ms-excel", "title": "PCBs.csv"}], "identifier": "https://doi.org/10.23719/1503181", "keyword": ["DSSTox", "Neurotoxic equivalent factor (NEF)", "PCB congeners", "Toxic equivalency factors (TEFs)", "neurotoxicity", "qsar"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2018-08-22", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1016/j.yrtph.2018.10.013"], "rights": null, "title": "Integrating data gap filling techniques: A case study predicting TEFs for neurotoxicity TEQs to facilitate the hazard assessment of polychlorinated biphenyls"}