{"@type": "dcat:Dataset", "accessLevel": "public", "bureauCode": ["009:25"], "contactPoint": {"@type": "vcard:Contact", "fn": "NIH/NCBI Data Team", "hasEmail": "mailto:info@ncbi.nlm.nih.gov"}, "description": "A compound of formula (I):wherein:Ring A is a nitrogen linked mono or bicyclic heterocyclic ring as defined within;R<1 >and R<2 >are independently C1-3alkyl optionally substituted by fluoro or chloro;or R<1 >and R<2 >together with the carbon atom to which they are attached, form a C3-5cycloalkyl ring optionally substituted by fluoro;R<3 >is defined within; andn is 0-5; wherein the values of R<3 >may be the same or different;or a pharmaceutically acceptable salt or an in vivo hydrolysable ester thereof is described. The use of compounds of formula (I) in the production of an elevation of PDH activity in a warm-blooded animal such as a human being are also described. Pharmaceutical compositions, methods and processes for preparation of compounds of formula (I) are detailed.", "distribution": [{"@type": "dcat:Distribution", "description": "Access the complete Patent AT-E399753-T1: [Translated] AMIDES AS PYRUVATE DEHYDROGENASE INHIBITORS on the official website.", "downloadURL": "https://pubchem.ncbi.nlm.nih.gov/patent/AT-E399753-T1", "mediaType": "text/html", "title": "Official Data Source"}], "identifier": "https://healthdata.gov/api/views/x757-9i2j", "issued": "2025-09-05", "keyword": ["chemistry", "innovation", "patent", "pubchem", "research"], "landingPage": "https://healthdata.gov/d/x757-9i2j", "modified": "2025-09-06", "programCode": ["009:066"], "publisher": {"@type": "org:Organization", "name": "National Center for Biotechnology Information (NCBI)"}, "theme": ["NIH"], "title": "Patent AT-E399753-T1: [Translated] AMIDES AS PYRUVATE DEHYDROGENASE INHIBITORS"}