{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Yong Ho Kim", "hasEmail": "mailto:kim.yongho@epa.gov"}, "description": "This dataset provides information on the gene regulation by single and repeated exposure to lower dose of burn pit smoke condensates and biological changes at 48 hrs post-exposure depending on different combustion conditions. The findings suggest that exposure to burn pit smoke condensates may impart a lasting adverse impact on human respiratory health, and the sustained effects depend on the waste source material and combustion condition. \n\nThis dataset is associated with the following publication:\nGhosh, A., K. Rogers, S. Gallant, S. Brocke, A. Speen, Y.H. Kim, I. Gilmour, S. Randell, and i. jaspers. Simulated burn pit smoke condensates cause sustained impact on human airway epithelial cell.   TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA,  204(1): 2-8, (2025).", "distribution": [{"accessURL": "https://dataverse.unc.edu/dataset.xhtml?persistentId=doi:10.15139/S3/W2ALPW", "title": "https://dataverse.unc.edu/dataset.xhtml?persistentId=doi:10.15139/S3/W2ALPW"}, {"accessURL": "https://github.com/UNC-CEMALB/Effects_of_simulated_military_burn_pit_condensate_exposure_in_human_airway_epithelial_cells-", "title": "https://github.com/UNC-CEMALB/Effects_of_simulated_military_burn_pit_condensate_exposure_in_human_airway_epithelial_cells-"}, {"accessURL": "https://github.com/UNC-CEMALB/Simulated-burn-pit-smoke-condensates-cause-sustained-impact-on-human-airway-epithelial-cells", "title": "https://github.com/UNC-CEMALB/Simulated-burn-pit-smoke-condensates-cause-sustained-impact-on-human-airway-epithelial-cells"}], "identifier": "https://doi.org/10.23719/1532205", "keyword": ["RNA sequencing", "burn pit waste", "human airway epithelial cells", "smokers"], "license": "https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html", "modified": "2024-10-18", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1093/toxsci/kfae161", "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879058"], "rights": null, "title": "Simulated burn pit smoke condensates cause sustained impact on human airway epithelial cells"}