{
  "accessLevel": "public",
  "bureauCode": [
    "020:00"
  ],
  "contactPoint": {
    "fn": "Michael Hornung",
    "hasEmail": "mailto:hornung.michael@epa.gov"
  },
  "description": "Data set includes optimized assay parameters and kinetic characterization for xenopus laevis deiodinase type 3 enzyme, and inhibition activity of 352 ToxCast chemicals against this enzyme. \n\nThis dataset is associated with the following publication:\nMayasich, S., J. Korte, J. Denny, P. Hartig, J. Olker, P. Degoey, J. O'Flanagan, S. Degitz, and M. Hornung. Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals.   TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA,  73: 105141, (2021).",
  "distribution": [
    {
      "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504033/200714_Mayasich_et_al_Xldio3%20screening%20data.xlsx",
      "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
      "title": "200714_Mayasich_et_al_Xldio3 screening data.xlsx"
    }
  ],
  "identifier": "https://doi.org/10.23719/1504033",
  "keyword": [
    "Enzyme activity",
    "Xenopus",
    "deiodinase",
    "thyroid"
  ],
  "license": "https://pasteur.epa.gov/license/sciencehub-license.html",
  "modified": "2019-06-19",
  "programCode": [
    "020:095"
  ],
  "publisher": {
    "name": "U.S. EPA Office of Research and Development (ORD)",
    "subOrganizationOf": {
      "name": "U.S. Environmental Protection Agency",
      "subOrganizationOf": {
        "name": "U.S. Government"
      }
    }
  },
  "references": [
    "https://doi.org/10.1016/j.tiv.2021.105141"
  ],
  "rights": null,
  "title": "Xenpous leavis deiodinase type 3 enzyme activity characterization and chemical screening data"
}