{
  "@type": "dcat:Dataset",
  "accessLevel": "public",
  "bureauCode": [
    "009:25"
  ],
  "contactPoint": {
    "@type": "vcard:Contact",
    "fn": "NIH/NCBI Data Team",
    "hasEmail": "mailto:info@ncbi.nlm.nih.gov"
  },
  "description": "Quinazoline derivatives of formula (I) for use in the treatment of proliferative diseases such as cancer and in the preparation of medicaments for use in the treatment of proliferative diseases, and to processes for their preparation, as well as pharmaceutical compositions containing, them as active ingredient. X is O or NR<SUP>6</SUP>; R<SUP>5 </SUP>is aryl or heteroaryl optionally substituted by 1, 2 or 3 substituents independently selected from halo, hydroxy, cyano, nitro, amino, C<SUB>1-4 </SUB>alkylamino, bis(C<SUB>1-4</SUB>alkyl)amino, C<SUB>1-4</SUB>alkyl, C<SUB>2-4 </SUB>alkenyl, C<SUB>2-4 </SUB>alkynyl, C<SUB>1-4 </SUB>alkoxy, C(O)NHR<SUP>17</SUP>, NHC(0)R<SUP>18 </SUP>and S(O)<SUB>p</SUB>R<SUP>19</SUP>where p is 0,1 or 2; The other substituents area as defined in claim 1.",
  "distribution": [
    {
      "@type": "dcat:Distribution",
      "description": "Access the complete Patent AT-E401080-T1: [Translated] (3-((CHINAZOLINE-4-YL)AMINO)-1H-PYRAZOLE-1- YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS AURORA KINASE INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER on the official website.",
      "downloadURL": "https://pubchem.ncbi.nlm.nih.gov/patent/AT-E401080-T1",
      "mediaType": "text/html",
      "title": "Official Data Source"
    }
  ],
  "identifier": "https://healthdata.gov/api/views/gsyu-vhbv",
  "issued": "2025-09-05",
  "keyword": [
    "chemistry",
    "innovation",
    "patent",
    "pubchem",
    "research"
  ],
  "landingPage": "https://healthdata.gov/d/gsyu-vhbv",
  "modified": "2025-09-06",
  "programCode": [
    "009:066"
  ],
  "publisher": {
    "@type": "org:Organization",
    "name": "National Center for Biotechnology Information (NCBI)"
  },
  "theme": [
    "NIH"
  ],
  "title": "Patent AT-E401080-T1: [Translated] (3-((CHINAZOLINE-4-YL)AMINO)-1H-PYRAZOLE-1- YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS AURORA KINASE INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER"
}