{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Sheau-Fung Thai", "hasEmail": "mailto:thai.sheau-fung@epa.gov"}, "description": "data sets included in this study:\n\nDifferential Expressed gene lists for nano Cu CuCl2 treated HepG2 cells through RNA sequencing.\nDifferential Expressed microRNA lists for nano Cu and CuCl2 treated HepG2 cells through small RNA sequencing.\nSequencing data was quantified using Partek annotation and the STAR-2.5.3a aligner, aligned to human genome hg19.  Normalization and contrast were performed using DESeq2.  MicroRNA expression was quantified with mirDeep2.  Benjamini-Hochberg method for multi-testing correcton was included in DESeq2. ", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518402/CuCl2%20miRNA%20lists.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "CuCl2 miRNA lists.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518402/DEG-0.05-result_CuCl2_0_25.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "DEG-0.05-result_CuCl2_0_25.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518402/DEG-0.05-result_CuCl2_0_5.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "DEG-0.05-result_CuCl2_0_5.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518402/DEG-0.05-result_CuCl2_1.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "DEG-0.05-result_CuCl2_1.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518402/DEG-0.05-result_CuCl2_3.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "DEG-0.05-result_CuCl2_3.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518402/DEG-0.05-result_Cu_10.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "DEG-0.05-result_Cu_10.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518402/DEG-0.05-result_Cu_1_25.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "DEG-0.05-result_Cu_1_25.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518402/DEG-0.05-result_Cu_2_5.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "DEG-0.05-result_Cu_2_5.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518402/DEG-0.05-result_Cu_5.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "DEG-0.05-result_Cu_5.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518402/nano%20Cu%20miRNA%20lists.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "nano Cu miRNA lists.xlsx"}], "identifier": "https://doi.org/10.23719/1518402", "keyword": ["HepG2 cells", "microRNA expression", "microRNA target filter analysis", "nano Cu", "signaling pathways", "transcriptomics"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2020-03-05", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": null, "rights": null, "title": "nano Cu microRNA DEG list "}