{"@type": "dcat:Dataset", "accessLevel": "public", "accrualPeriodicity": "irregular", "bureauCode": ["026:00"], "contactPoint": {"@type": "vcard:Contact", "fn": "GeneLab Outreach", "hasEmail": "mailto:genelab-outreach@lists.nasa.gov"}, "description": "Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and microRNA microarray in dauer larvae of Caenorhabditis elegans (C. elegans) that endured spaceflight environment and space radiations environment during 16.5-day Shenzhou-8 space mission were performed. In our study wild type and ced-1 mutant strains of C.elegans endured three conditions during shenzhou-8 spaceflight mission including spaceflight static condition(ss) spaceflight 1-g centrifugal condition(sc) and ground control condition(gc). Limited to the quantity of worm samples we performed technical-repeat test but not sample-repeat test.Accordingly xef xbc x8csix miRNA microarrays were performed.", "distribution": [{"@type": "dcat:Distribution", "description": "GeneLab Study Page", "downloadURL": "https://genelab-data.ndc.nasa.gov/genelab/accession/GLDS-166", "format": "HTML", "mediaType": "text/html", "title": "Synergistic effects of space radiation and microgravity (miRNA WT and ced-1 mutant)"}], "identifier": "nasa_genelab_GLDS-166_jis2-9sk8", "issued": "2021-05-21", "keyword": ["absorbed-radiation-dose", "data-collection", "labeling", "normalization-data-transformation", "nucleic-acid-hybridization", "rna-extraction", "sample-collection", "weightlessness"], "landingPage": "https://data.nasa.gov/dataset/synergistic-effects-of-space-radiation-and-microgravity-mirna-wt-and-ced-1-mutant", "license": "http://www.usa.gov/publicdomain/label/1.0/", "modified": "2025-04-23", "programCode": ["026:005"], "publisher": {"@type": "org:Organization", "name": "National Aeronautics and Space Administration"}, "theme": ["Earth Science"], "title": "Synergistic effects of space radiation and microgravity (miRNA WT and ced-1 mutant)"}