{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Keith Houck", "hasEmail": "mailto:houck.keith@epa.gov"}, "description": "HT-H295R data was downloaded using the ToxCast pipeline (tcpl) R package and is publicly available. Multi-concentration level 0 data from invitrodb (version 3.1) were downloaded and converted from g/ml into micromolar concentrations prior to calculation of mMds and data simulation (Supplemental Data 1). \n\nThis dataset is associated with the following publication:\nHaggard, D., W. Setzer, R. Judson, and K. Friedman. Development of a prioritization method for chemical-mediated effects on steroidogenesis using an integrated statistical analysis of high-throughput H295R data.   REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, USA, 109: 104510, (2019).", "distribution": [{"accessURL": "https://cran.r-project.org/web/packages/tcpl/index.html", "title": "https://cran.r-project.org/web/packages/tcpl/index.html"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1503880/Supplemental_Haggard_et_al_mahalanobis_prioritization.zip", "mediaType": "application/x-zip-compressed", "title": "Supplemental_Haggard_et_al_mahalanobis_prioritization.zip"}], "identifier": "https://doi.org/10.23719/1503880", "keyword": ["High throughput screening", "Steriodogenesis", "ToxCast", "chemical prioritization", "endocrine disruption", "high throughput toxicology"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2019-05-21", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1016/j.yrtph.2019.104510"], "rights": null, "title": "Prioritization of chemicals for effects on steroidogenesis using an integrated statistical approach to high-throughput H295R data"}