{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Elaina Kenyon", "hasEmail": "mailto:kenyon.elaina@epa.gov"}, "describedBy": "https://pasteur.epa.gov/uploads/10.23719/1407661/documents/DataDictionary_PediatricScalingVariability.pdf", "describedByType": "application/pdf", "description": "This dataset contains physiologically-based (PBPK) model code and parameter settings supporting the manuscript titled \"THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT PHARMACOKINETIC OUTCOMES IN CHILDREN:  A CASE STUDY USING BROMODICHLOROMETHANE (BDCM)\". \n\nThis dataset is associated with the following publication:\nKenyon, E., J. Lipscomb, R. Pegram, B. George, and R. Hines. THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT PHARMACOKINETIC OUTCOMES IN CHILDREN:  A CASE STUDY USING BROMODICHLOROMETHANE (BDCM).   TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA,  167(2): 347-359, (2019).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1407661/ModelFile_BDCM_peds.pdf", "mediaType": "application/pdf", "title": "ModelFile_BDCM_peds.pdf"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1407661/ModelParameters_PedsScalingVariability.pdf", "mediaType": "application/pdf", "title": "ModelParameters_PedsScalingVariability.pdf"}], "identifier": "https://doi.org/10.23719/1407661", "keyword": ["age-related susceptibility", "bromodichloromethane", "children", "global sensitivity analysis", "in vitro to in vivo extrapolation (IVIVE)", "pediatric", "scaling factors", "trihalomethanes", "variability"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2017-10-02", "programCode": ["020:096"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1093/toxsci/kfy236", "https://pasteur.epa.gov/uploads/10.23719/1407661/documents/PedsScalingFactorVariability_ModelSettings%26Inputs.pdf", "https://pasteur.epa.gov/uploads/10.23719/1407661/documents/SupplementalData_PedsScalingVariability.pdf"], "rights": null, "title": "Impact of Scaling Factor Variability on Risk Relevant Outcomes in Children"}