{"@type": "dcat:Dataset", "accessLevel": "public", "bureauCode": ["009:25"], "contactPoint": {"@type": "vcard:Contact", "fn": "NIH/NCBI Data Team", "hasEmail": "mailto:info@ncbi.nlm.nih.gov"}, "description": "1. Claims for the Contracting States : BE CH DE GB IT LI LU NL SE Pyroglutamic derivative, characterized in that it corresponds to the following formula (I) :  see diagramm : EP0135444,P15,F2  in which : Y and Z have the following meanings : Y : -CO CH2 Cl  see diagramm : EP0135444,P15,F3   see diagramm : EP0135444,P15,F4  Z : -COO CH3 ; Y : -CO CH2 Cl Z : -COO CH3 ;  see diagramm : EP0135444,P15,F5  Z : -COO CH3 ;  see diagramm : EP0135444,P15,F6  Z : -COO CH3 ;  see diagramm : EP0135444,P15,F7  Z : -COO CH3 ;  see diagramm : EP0135444,P16,F1  Z : -COOH ; Y : -COCH2 -Cl   Z : -COOH 1. Claims for the Contracting State : AT Process for preparing a pyroglutamic derivative of the following formula (I) :  see diagramm : EP0135444,P17,F2  in which : Y and Z have the following meanings : Y : -CO CH2 Cl  see diagramm : EP0135444,P17,F3   see diagramm : EP0135444,P17,F4  Z : -COO CH3 ; Y : -CO CH2 Cl Z : -COO CH3 ;  see diagramm : EP0135444,P17,F5  Z : -COO CH3 ;  see diagramm : EP0135444,P17,F6  Z : -COO CH3 ;  see diagramm : EP0135444,P17,F7  Z : -COO CH3 ;  see diagramm : EP0135444,P17,F8  Z : -COOH ; Y : -COCH2 -Cl    Z : -COOH characterized in that a compound of the following formula (II) :  see diagramm : EP0135444,P17,F9  in which W is chosen from an ester group corresponding to Z defined above, or -COOSiMe3 group ; is reacted with an acylating agent such as an organic halide of formula Y-Hal, where Hal = halogen, especially chlorine, and where Y is defined as above, or with diketene ; and, in the case where W is a -COOSiMe3 group, the resulting intermediate product is converted to the corresponding acid or ester, for example by a hydrolysis or alcoholysis of this product.", "distribution": [{"@type": "dcat:Distribution", "description": "Access the complete Patent AT-E40113-T1: [Translated] PYROGLUTAMIC ACID DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE,INTERMEDIATE PRODUCTS AND FUNCIDAL AND/OR BACTERICIDE AGENTS, AND COSMETIC OR PHARMACEUTICAL AGENTS. on the official website.", "downloadURL": "https://pubchem.ncbi.nlm.nih.gov/patent/AT-E40113-T1", "mediaType": "text/html", "title": "Official Data Source"}], "identifier": "https://healthdata.gov/api/views/gybv-h86i", "issued": "2025-09-05", "keyword": ["chemistry", "innovation", "patent", "pubchem", "research"], "landingPage": "https://healthdata.gov/d/gybv-h86i", "modified": "2025-09-06", "programCode": ["009:066"], "publisher": {"@type": "org:Organization", "name": "National Center for Biotechnology Information (NCBI)"}, "theme": ["NIH"], "title": "Patent AT-E40113-T1: [Translated] PYROGLUTAMIC ACID DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE,INTERMEDIATE PRODUCTS AND FUNCIDAL AND/OR BACTERICIDE AGENTS, AND COSMETIC OR PHARMACEUTICAL AGENTS."}