{"accessLevel": "public", "bureauCode": ["010:12"], "contactPoint": {"@type": "vcard:Contact", "fn": "Erik Hofmeister", "hasEmail": "mailto:ehofmeister@usgs.gov"}, "description": "Following building an aerosol exposure chamber in which we could expose domesticated zebra finches, we examined the effects of exposure to aerosolized Permanone\u00ae 30:30 insecticide (permethrin and piperonyl butoxide in soy oil vehicle) at ~103-106 x potential environmental concentrations on the response to experimental challenge with West Nile virus (WNV).  Compared to vehicle control birds, WNV outcome was unchanged (65% of birds produced a viremia) in the \u2018low\u2019 exposure (9.52 mg/m3\u00b13.13 SD permethrin) group, but reduced in the \u2018high\u2019 exposure (mean 376.5 mg/m3\u00b127.9 SD permethrin) group (30% were viremic) (p < 0.05). After clearing WNV infection, birds treated with Permanone regained less body mass than vehicle treated birds (p < 0.001). Our study suggests that exposure to aerosolized Permanone insecticide at levels exceeding typical application rates has the potential to not change or mildly enhance a bird\u2019s resistance to WNV.", "distribution": [{"@type": "dcat:Distribution", "accessURL": "https://doi.org/10.5066/F7TM78KV", "description": "Landing page for access to the data", "format": "XML", "mediaType": "application/http", "title": "Digital Data"}, {"@type": "dcat:Distribution", "description": "The metadata original format", "downloadURL": "https://data.usgs.gov/datacatalog/metadata/USGS.5a09b689e4b09af898c94770.xml", "format": "XML", "mediaType": "text/xml", "title": "Original Metadata"}], "identifier": "http://datainventory.doi.gov/id/dataset/USGS_5a09b689e4b09af898c94770", "keyword": ["Insecticide", "Laboratory animal model", "Permanone", "USGS:5a09b689e4b09af898c94770", "disease", "pesticide and herbicide contamination", "toxicology"], "modified": "2020-10-16T00:00:00Z", "publisher": {"@type": "org:Organization", "name": "U.S. Geological Survey"}, "theme": ["geospatial"], "title": "An examination of the effect of aerosolized Permanone insecticide on zebra finch susceptibility to West Nile virus: Data"}