{"@type": "dcat:Dataset", "accessLevel": "public", "bureauCode": ["009:25"], "contactPoint": {"@type": "vcard:Contact", "fn": "NIH/NCBI Data Team", "hasEmail": "mailto:info@ncbi.nlm.nih.gov"}, "description": "The present invention relates to pre-formulations comprising low viscosity, non-liquid crystalline, mixtures of:a) at least one neutral diacyl lipid and/or at least one tocopherol;b) at least one phospholipid;c) at least one biocompatible, oxygen containing, low viscosity organic solvent;wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture and wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The preformulations are suitable for generating parenteral, non-parenteral and topical depot compositions for sustained release of active agents. The invention additionally relates to a method of delivery of an active agent comprising administration of a preformulation of the invention, a method of treatment comprising administration of a preformulation of the invention and the use of a preformulation of the invention in a method for the manufacture of a medicament.", "distribution": [{"@type": "dcat:Distribution", "description": "Access the complete Patent AT-E401054-T1: [Translated] LIQUID DEPOSIT FORMULATIONS on the official website.", "downloadURL": "https://pubchem.ncbi.nlm.nih.gov/patent/AT-E401054-T1", "mediaType": "text/html", "title": "Official Data Source"}], "identifier": "https://healthdata.gov/api/views/c9ud-wvv6", "issued": "2025-09-05", "keyword": ["chemistry", "innovation", "patent", "pubchem", "research"], "landingPage": "https://healthdata.gov/d/c9ud-wvv6", "modified": "2025-09-06", "programCode": ["009:066"], "publisher": {"@type": "org:Organization", "name": "National Center for Biotechnology Information (NCBI)"}, "theme": ["NIH"], "title": "Patent AT-E401054-T1: [Translated] LIQUID DEPOSIT FORMULATIONS"}