{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Thomas Knudsen", "hasEmail": "mailto:knudsen.thomas@epa.gov"}, "description": "Biomarker Image Cytometry. The cell-level frequency of NK2 Homeobox 1 (NKX2-1), Keratin 7 (KRT7), and Thyroglobulin (TG) protein staining were quantitatively evaluated by high-content imaging across huThyrEC cell line variants (1-4) in two medium formulations (huThyrEC and h7H) for verification of thyroid follicular epithelial cell enrichment. Data are the % positive expression frequency (mean \u00b1 SD) of two replicates. \n\nThis dataset is associated with the following publication:\nHopperstad, K., T. Truschel, T. Wahlicht, W. Stewart, A. Eicher, T. May, and C. Deisenroth. Characterization of Novel Human Immortalized Thyroid Follicular Epithelial Cell Lines.   Applied In Vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, USA, 7(2): 39-49, (2021).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1520918/AIVT_EPA-InSCREENeX_Tables_All_v1.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "AIVT_EPA-InSCREENeX_Tables_All_v1.xlsx"}], "identifier": "https://doi.org/10.23719/1520918", "keyword": ["endocrine toxicology", "in vitro toxicology", "organotypic culture model", "thyroid", "tipping points", "vEmbryo", "virtual embryo", "virtual tissues"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2020-09-11", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1089/aivt.2020.0027"], "rights": null, "title": "Characterization of Novel Human Immortalized Thyroid Follicular Epithelial Cell Lines"}