{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Keith Houck", "hasEmail": "mailto:houck.keith@epa.gov"}, "description": "Table S1. All chemicals and AC50 from invitrodb v3 for human FACTORIAL-TRANS assay endpoints.\nTable S2. Agreement with OECD reference AR agonists.\nTable S3. Agreement with OECD reference ER agonists.\nTable S4. Agreement with OECD reference ER antagonists.\nTable S5. Summary results of 191 test chemicals AC50 agreements\nTable S6. Curve fitting parameters for all endpoints.\nWord File: Supplementary data. \n\nThis dataset is associated with the following publication:\nHouck, K., A. Simha, A. Bone, J. Doering, S. Vliet, C. LaLone, A. Medvedev, and S. Makarov. Evaluation of a Multiplexed, Multispecies Nuclear Receptor Assay for Chemical Hazard Assessment.   TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 72: 105016, (2021).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518765/Supplemental%20Data%2C%20S1.docx", "mediaType": "application/vnd.openxmlformats-officedocument.wordprocessingml.document", "title": "Supplemental Data, S1.docx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518765/TableS1.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "TableS1.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518765/TableS2.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "TableS2.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518765/TableS3.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "TableS3.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518765/TableS4.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "TableS4.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518765/TableS5.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "TableS5.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1518765/TableS6.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "TableS6.xlsx"}], "identifier": "https://doi.org/10.23719/1518765", "keyword": ["Endocrine Disruptors", "High throughput screening", "ToxCast", "ecotoxicoloty", "high throughput toxicology", "multiplexed assay", "nuclear receptor", "reporter gene", "zebrafish"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2020-09-21", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1016/j.tiv.2020.105016"], "rights": null, "title": "Evaluation of a Multiplexed, Multispecies Nuclear Receptor Assay for Chemical Hazard Assessment"}