{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Jonathan Haselman", "hasEmail": "mailto:haselman.jon@epa.gov"}, "description": "This dataset contains in vitro and in vivo biochemical and apical (i.e., growth/development) data pertaining to iodotyrosine deiodinase inhibition in the African clawed frog (Xenopus laevis). \n\nThis dataset is associated with the following publication:\nHaselman, J., J. Olker, P. Kosian, J. Korte, J. Denny, J. Tietge, M. Hornung, and S. Degitz. Characterization of the Mechanistic Linkages Between Iodothyronine Deiodinase Inhibition and Impaired Thyroid-Mediated Growth and Development in Xenopus Laevis Using Iopanoic Acid.   TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA,  187(1): 139-149, (2022).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1522991/Haselman_et_al_2021_IOP_data_SciHub.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Haselman_et_al_2021_IOP_data_SciHub.xlsx"}], "identifier": "https://doi.org/10.23719/1522991", "keyword": ["adverse outcome pathway", "ecotoxicology", "endocrine disruption", "thyroid"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2021-07-06", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1093/toxsci/kfac014"], "rights": null, "title": "Effects of deiodinase inhibition on amphibian metamorphosis"}