{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Mark Higuchi", "hasEmail": "mailto:higuchi.mark@epa.gov"}, "description": "Whole transcriptomics dose response data is collected and storedthrough public facing Gene Expression Omnibus database.\nRaw collected viability/cytotoxicity data for each chemical are collected and presented on separate spreadsheets. Portions of this dataset are inaccessible because: The transcriptomics full data file is too large to be uploaded alone onto ScienceHub, impeding ease of access. They can be accessed through the following means: Raw and processed transcriptomics data is available through Gene Expression Omnibus (GEO, https://www.ncbi.nlm.nih.gov/geo/) under accession GSE199794. Format: The full transcriptomics data set for all chemical conditions tested. \n\nThis dataset is associated with the following publication:\nSpeen, A., J. Murray, T. Krantz, D. Davies, P. Evansky, J. Harrill, L. Everett, J. Bundy, L. Dailey, W. Zander, E. Carlsten, M. Monsees, J. Hill, J. Zavala, and M. Higuchi. Benchmark Dose Modeling Approaches for Volatile Organic Chemicals using a Novel Air-Liquid Interface In Vitro Exposure System.   TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA,  188(1): 88-107, (2022).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524251/1%2C3-butadiene%20Sample%20ID%20and%20exposure%20conditions.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "1,3-butadiene Sample ID and exposure conditions.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524251/1-Bromopropane%20Sample%20ID%20and%20Exposure%20Conditions.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "1-Bromopropane Sample ID and Exposure Conditions.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524251/Acetaldehyde%20Sample%20ID%20and%20Exposure%20Conditions.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Acetaldehyde Sample ID and Exposure Conditions.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524251/Acrolein%20Sample%20ID%20and%20Exposure%20Conditions.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Acrolein Sample ID and Exposure Conditions.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524251/Carbon%20Tetrachloride%20Sample%20ID%20and%20Exposure%20Conditions.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Carbon Tetrachloride Sample ID and Exposure Conditions.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524251/Dichloromethane%20Sample%20ID%20and%20Exposure%20Conditions1.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Dichloromethane Sample ID and Exposure Conditions1.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524251/Formaldehyde%20Sample%20ID%20and%20Exposure%20Conditions.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Formaldehyde Sample ID and Exposure Conditions.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1524251/Trichloroethylene%20Sample%20ID%20and%20Exposure%20Conditions.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Trichloroethylene Sample ID and Exposure Conditions.xlsx"}], "identifier": "https://doi.org/10.23719/1524251", "keyword": ["Volatile organic compound (VOC)", "airway epithelial cells", "transcriptomics"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2021-11-16", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1093/toxsci/kfac040"], "rights": null, "title": "Benchmark Dose Modeling Approaches for Volatile Organic Chemicals using a Novel Air-Liquid Interface In Vitro Exposure System"}