{"@type": "dcat:Dataset", "accessLevel": "public", "bureauCode": ["009:25"], "contactPoint": {"@type": "vcard:Contact", "fn": "NIH", "hasEmail": "mailto:info@nih.gov"}, "description": "Background\n          Capping protein (CP), a heterodimer of \u03b1 and \u03b2 subunits, is found in all eukaryotes. CP binds to the barbed ends of actin filaments in vitro and controls actin assembly and cell motility in vivo. Vertebrates have three isoforms of CP\u03b2 produced by alternatively splicing from one gene; lower organisms have one gene and one isoform.\n        \n        \n          Results\n          We isolated genomic clones corresponding to the \u03b2 subunit of mouse CP and identified its chromosomal location by interspecies backcross mapping.\n        \n        \n          Conclusions\n          The CP\u03b2 gene (Cappb1) mapped to Chromosome 4 between Cdc42 and D4Mit312. Three mouse mutations, snubnose, curly tail, and cribriform degeneration, map in the vicinity of the \u03b2 gene.", "distribution": [{"@type": "dcat:Distribution", "description": "Visit the original government dataset for complete information, documentation, and data access.", "downloadURL": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC29085/", "mediaType": "text/html", "title": "Official Government Data Source"}], "identifier": "https://healthdata.gov/api/views/6sq8-ch4q", "issued": "2025-07-13", "keyword": ["actin-capping-protein", "chromosome-4", "gene-mapping", "mouse-genome", "nih"], "landingPage": "https://healthdata.gov/d/6sq8-ch4q", "modified": "2025-09-06", "programCode": ["009:033"], "publisher": {"@type": "org:Organization", "name": "National Institutes of Health"}, "theme": ["NIH"], "title": "Mapping of the Mouse Actin Capping Protein Beta Subunit Gene"}