{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Edward Pennington", "hasEmail": "mailto:pennington.edward@epa.gov"}, "description": "The metadata provided in this entry highlights controlled exposure of healthy young adults to 0.07 ppm ozone for 6.6 hours which causes pulmonary function decline (decreased FEV1/FVC) and increased airway inflammation (%PMN neutrophils) compared to clean air. This study also indicates these effects are accompanied by increased respiratory symptoms, highlighting the effects of prolonged exposure at current air quality standards. \n\nThis dataset is associated with the following publication:\nPennington, E., J. Pulczinski, M. Case, J. Griffin, N. Alexis , C. Robinette, A. Chelminski, A. Davis, N. Miller, A. Ghio, D. Diazsanchez, and A. Rappold. Lung Function and Inflammation in Healthy Young Adults After 6.6 Hours of 0.07 ppm Ozone Exposure.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. American Thoracic Society, New York, NY, USA,  124387, (2026).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/d-86h9/Lung%20Function%20and%20Inflamm%200.07%20ppm%20Ozone%20-%20METADATA.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Lung Function and Inflamm 0.07 ppm Ozone - METADATA.xlsx"}], "identifier": "https://doi.org/10.23719/d-86h9", "keyword": ["Exercise", "Ozone", "air quality", "inflammation", "pulmonary function"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2026-04-08", "programCode": ["020:000"], "publisher": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}, "references": ["https://doi.org/10.1016/j.envres.2026.124387"], "rights": null, "spatial": "-79.3588,35.6031,-78.3949,36.1494", "title": "Lung Function and Inflamm 0.07 ppm Ozone - METADATA"}