{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Carlie Lalone", "hasEmail": "mailto:lalone.carlie@epa.gov"}, "description": "All data associated with publication are publicly available online at https://datadryad.org/ by searching doi:10.5061/dryad.2tg6967\nUpon accessing data on datadryad.org:\nData descriptions are found with Supplemental Data presented in the pdf (Supplementary Data.pdf (600.4 Kb)).\nData description of supplemental Data (Supplementary Data File.xlsx (1.167 Mb)) is provided below:\nTabs one, two, and three contain the raw data for acetylcholinesterase (AChE) Level 1 (Figure 1A), Level 2 (Figure 1B), and Level 3 (Table 2) SeqAPASS analysis, respectively. Tab four contains the raw data for AChE Level 3 improved SeqAPASS analysis (Table 5). Tabs five, six, and seven contain the raw data for ecdysone receptor (EcR) Level 1 (Figure 2A), Level 2 (Figure 2B), and Level 3 (Table 6) SeqAPASS analysis, respectively. Tab eight contains the raw data for EcR Level 3 improved SeqAPASS analysis (Table 8). \n\nThis dataset is associated with the following publication:\nDoering, J., S. Lee, K. Kristiansen, L. Evenseth, M. Barron, I. Sylte, and C. LaLone. In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool..   TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA,  166(1): 131-145, (2018).", "distribution": [{"accessURL": "https://datadryad.org/", "title": "https://datadryad.org/"}], "identifier": "https://doi.org/10.23719/1432264", "keyword": ["adverse outcome pathway", "cross-species extrapolation", "ecotoxicology", "honey bee", "networks", "screening and prioritization"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2018-07-30", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1093/toxsci/kfy186"], "rights": null, "title": "In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) "}