{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Sheau-Fung Thai", "hasEmail": "mailto:thai.sheau-fung@epa.gov"}, "description": "Dataset for 'Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells' by Sheau-Fung Thai et al., accepted by Materials Express. \n\nFor the data set:\n\nDEG: differentially expressed genes\n33-MWCNT: parent MWCNT\n55-OH-MWCNT: MWCNT modified with -OH group\n66-COOH-MWCNT: MWCNT modified with -COOH group.\nMWCNT_66_30 means cells treated with 66-COOH-MWCNT at 30 microgram/ml. \n\nThis dataset is associated with the following publication:\nThai, S., C. Jones, B. Robinette, H. Ren, B. Vallanat, A. Astriab Fisher, and K. Kitchin. Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells.   Materials Express. American Scientific Publishers, VALENCIA, CA, USA, 14(3): 403-415, (2024).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2033_1.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "MWCNT 33_1.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2033_10.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "MWCNT 33_10.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2033_3.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "MWCNT 33_3.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2055_10-1.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "MWCNT 55_10-1.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2055_10.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "MWCNT 55_10.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2055_30-1.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "MWCNT 55_30-1.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2055_30.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "MWCNT 55_30.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2066_10.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "MWCNT 66_10.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2066_30.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "MWCNT 66_30.xlsx"}], "identifier": "https://doi.org/10.23719/1529906", "keyword": ["HepG2 cells", "Multi-wall carbon nanotubes", "Target Filter Analysis", "acute phase response signaling", "cholesterol biosynthesis pathways", "microrna", "oxidative stress", "signaling pathways", "transcriptomics"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2022-04-06", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1166/mex.2024.2641"], "rights": null, "title": "Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells "}