{
  "accessLevel": "public",
  "bureauCode": [
    "020:00"
  ],
  "contactPoint": {
    "fn": "Daniel Villeneuve",
    "hasEmail": "mailto:villeneuve.dan@epa.gov"
  },
  "description": "Table of contents\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\nTable S1\tDNT inventory\tList of sources and associated data collected for the development of the Bayesian hierarchical model. \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\nTable S2\tData collection\tIt contains the compiled raw data.\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\nTable S3\tFinal dataset\tIt contains data after curation agreed to be included in the Bayesian hierarchical model.\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\nTable S4\tList of encoders\tMachine readable format used to encode the data.\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\nTable S5\tMachine readable\tThe final dataset translated into a machine readable file using the encoders listed above.\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\nTable S6\tResults for DNT\tBased on the cut-offs derived from the results themselves, three classes of DNT are proposed (low, medium and high predicted probability). Results are summarised accordingly. \n\nThis dataset is associated with the following publication:\nSpinu, N., M. Cronin, J. Lao, A. Bal-Price, I. Campia, S. Enoch, J. Madden, L. Lagares, M. Novic, D. Pamies, S. Scholz, D. Villeneuve, and A. Worth. Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network.   Computational Toxicology. Elsevier B.V., Amsterdam,  NETHERLANDS, 21: 100206, (2022).",
  "distribution": [
    {
      "accessURL": "https://www.sciencedirect.com/science/article/pii/S2468111321000529?via%3Dihub#s0070",
      "title": "https://www.sciencedirect.com/science/article/pii/S2468111321000529?via%3Dihub#s0070"
    }
  ],
  "identifier": "https://doi.org/10.23719/1526406",
  "keyword": [
    "Adverse Outcome Pathways (AOPs)",
    "New Approach Methods (Alternatives to Animal Testi",
    "computational toxicology",
    "developmental neurotoxicity",
    "screening and prioritization"
  ],
  "license": "https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html",
  "modified": "2022-05-04",
  "programCode": [
    "020:000"
  ],
  "publisher": {
    "name": "U.S. EPA Office of Research and Development (ORD)",
    "subOrganizationOf": {
      "name": "U.S. Environmental Protection Agency",
      "subOrganizationOf": {
        "name": "U.S. Government"
      }
    }
  },
  "references": [
    "https://doi.org/10.1016/j.comtox.2021.100206"
  ],
  "rights": null,
  "title": "Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network"
}