{"@type": "dcat:Dataset", "accessLevel": "public", "accrualPeriodicity": "irregular", "bureauCode": ["026:00"], "contactPoint": {"@type": "vcard:Contact", "fn": "GeneLab Outreach", "hasEmail": "mailto:genelab-outreach@lists.nasa.gov"}, "description": "In prospective human exploration of outer space the need to maintain a species over several generations under changed gravity conditions may arise. This paper reports the analysis of the third generation of fruit fly Drosophila melanogaster obtained during the 44.5-day space flight (Foton-M4 satellite 2014 Russia) followed by the fourth generation on Earth and the fifth generation under conditions of a 12-day space flight (2014 in the Russian Segment of the ISS). The obtained results show that it is possible to obtain the third-fifth generations of a complex multicellular Earth organism under changed gravity conditions (in the cycle weightlessness - Earth - weightlessness) which preserves fertility and normal development. However there were a number of changes in the expression levels and content of cytoskeletal proteins that are the key components of the spindle apparatus and the contractile ring of cells.", "distribution": [{"@type": "dcat:Distribution", "description": "GeneLab Study Page", "downloadURL": "https://genelab-data.ndc.nasa.gov/genelab/accession/GLDS-96", "format": "HTML", "mediaType": "text/html", "title": "The development of Drosophila melanogaster during space flight"}], "identifier": "nasa_genelab_GLDS-96_8wbt-pycv", "issued": "2021-05-21", "keyword": ["data-transformation", "genelab-rnaseq-data-processing-protocol", "generation", "growth-protocol", "library-construction", "nucleic-acid-extraction", "nucleic-acid-sequencing", "sequence-analysis-data-transformation", "spaceflight", "time"], "landingPage": "https://data.nasa.gov/dataset/the-development-of-drosophila-melanogaster-during-space-flight", "license": "http://www.usa.gov/publicdomain/label/1.0/", "modified": "2025-04-23", "programCode": ["026:005"], "publisher": {"@type": "org:Organization", "name": "National Aeronautics and Space Administration"}, "theme": ["Earth Science"], "title": "The development of Drosophila melanogaster during space flight"}