{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Michael Hornung", "hasEmail": "mailto:hornung.michael@epa.gov"}, "description": "This dataset is from screening 94 diverse chemicals for estrogen receptor (ER) activation in a competitive rainbow trout ER binding assay and a trout liver slice vitellogenin mRNA expression assay. \n\nThis dataset is associated with the following publication:\nHornung, M., M. Tapper, J. Denny, B. Sheedy, R. Erickson, T. Sulerud, R. Kolanczyk, and P. Schmieder. Avoiding false positives and optimizing identification of true negatives in estrogen receptor binding and agonist/antagonist assays.   Applied In vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, USA, 3(2): 163-181, (2017).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/472/Trout_ER_Antagonism_Data.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Trout_ER_Antagonism_Data.xlsx"}], "identifier": "A-8czj-472", "keyword": ["antagonist", "competitive binding", "estrogen receptor", "in vitro", "rainbow trout", "vitellogenin"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2017-01-11", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1089/aivt.2016.0021"], "rights": null, "title": "Rainbow trout estrogen receptor (ER) competitive bindng and vitellogenin induction agonism/antagonism data for 94 chemicals"}