{"@type": "dcat:Dataset", "accessLevel": "public", "bureauCode": ["009:25"], "contactPoint": {"@type": "vcard:Contact", "fn": "NIH", "hasEmail": "mailto:info@nih.gov"}, "description": "Our current state of knowledge on noninvasive positive pressure\t\t\t ventilation (NPPV) and technical aspects are discussed in the present review.\t\t\t In patients with chronic obstructive pulmonary disease, NPPV can be considered\t\t\t a valid therapeutic option to prevent endotracheal intubation. Evidence\t\t\t suggests that, before eventual endotracheal intubation, NPPV should be\t\t\t considered as first-line intervention in the early phases of acute exacerbation\t\t\t of chronic obstructive pulmonary disease. Small randomized and non-randomized\t\t\t studies on the application of NPPV in patients with acute hypoxaemic\t\t\t respiratory failure showed promising results, with reduction in complications\t\t\t such as sinusitis and ventilator-associated pneumonia, and in the duration of\t\t\t intensive care unit stay. The conventional use of NPPV in hypoxaemic acute\t\t\t respiratory failure still remains controversial, however. Large randomized\t\t\t studies are still needed before extensive clinical application in this\t\t\t condition.", "distribution": [{"@type": "dcat:Distribution", "description": "Visit the original government dataset for complete information, documentation, and data access.", "downloadURL": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC137248/", "mediaType": "text/html", "title": "Official Government Data Source"}], "identifier": "https://healthdata.gov/api/views/qkqp-rv8m", "issued": "2025-07-14", "keyword": ["acute-respiratory-failure", "copd-exacerbation", "critical-care", "nih", "noninvasive-ventilation"], "landingPage": "https://healthdata.gov/d/qkqp-rv8m", "modified": "2025-09-06", "programCode": ["009:032"], "publisher": {"@type": "org:Organization", "name": "National Institutes of Health"}, "theme": ["NIH"], "title": "Noninvasive positive pressure ventilation as treatment for acute\t\t  respiratory failure in critically ill patients"}