{"@type": "dcat:Dataset", "accessLevel": "public", "bureauCode": ["009:25"], "contactPoint": {"@type": "vcard:Contact", "fn": "NIH", "hasEmail": "mailto:info@nih.gov"}, "description": "Results and new hypotheses in animal models often stimulate\t\t\t development of new paradigms in how we view rheumatoid arthritis (RA). The\t\t\t complexity of RA does, however, eventually lead to the rejection of these\t\t\t hypotheses. Here, it is argued that the large number of so-far described animal\t\t\t models, when taken together, also reveals a complex disease. Fortunately,\t\t\t detailed study of each of the animal models will reveal this complexity, and\t\t\t may also be helpful in elucidating the complexity of the human disease. Benoist\t\t\t and Mathis [1] recently contributed a new animal model in\t\t\t which an autoimmune response to a ubiquitous antigen leads to an\t\t\t antibody-mediated inflammatory attack in the joints. It is argued that this new\t\t\t model, as with other animal models, is unlikely to explain RA, but it will add\t\t\t to the tools available to reveal the complexity of RA.", "distribution": [{"@type": "dcat:Distribution", "description": "Visit the original government dataset for complete information, documentation, and data access.", "downloadURL": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC129997/", "mediaType": "text/html", "title": "Official Government Data Source"}], "identifier": "https://healthdata.gov/api/views/vtde-izs7", "issued": "2025-07-14", "keyword": ["animal-models", "autoimmune-disease", "joint-inflammation", "nih", "rheumatoid-arthritis"], "landingPage": "https://healthdata.gov/d/vtde-izs7", "modified": "2025-09-06", "programCode": ["009:033"], "publisher": {"@type": "org:Organization", "name": "National Institutes of Health"}, "theme": ["NIH"], "title": "Rheumatoid arthritis viewed using a headache paradigm"}