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Federal
The Arabidopsis spaceflight transcriptome: a comparison of whole plants to discrete root hypocotyl and shoot responses to the orbital environment
National Aeronautics and Space Administration —
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches... -
Federal
MESSAGE 2 space experiment with Rhodospirillum rubrum S1H
National Aeronautics and Space Administration —
R. rubrum S1H inoculated on solid agar rich media was sent to the ISS in October 2003 (MESSAGE-part 2 experiment). After 10 days flight R. rubrum cultures returned... -
Federal
The Arabidopsis spaceflight transcriptome: a comparison of whole plants to discrete root hypocotyl and shoot responses to the orbital environment
National Aeronautics and Space Administration —
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 cGy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 cGy RNA is isolated and labeled using a T7... -
Federal
Expression data from C. elegans
National Aeronautics and Space Administration —
We used microarrays to investigate the effects of microgravity and space radiation on the genome-wide expression of the C. elegans. Three technical replicates of wild... -
Federal
Identifying radiation exposure biomarkers from mouse blood transcriptome
National Aeronautics and Space Administration —
Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological... -
Federal
IMR90 radiation bystander time-course experiment 0.5Gy alpha particle
National Aeronautics and Space Administration —
The radiation bystander effect is an important component of the overall biological response of tissues and organisms to ionizing radiation. Little is known about the... -
Federal
Response of human lymphoblastoid cells to activated medium
National Aeronautics and Space Administration —
Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiaed cells resuspended in fresh untreated RPMI 1640 medium with cells resuspended in... -
Federal
Expression data from SPHINX (SPaceflight of Huvec: an INtegrated eXperiment)
National Aeronautics and Space Administration —
Changes in the physical environment modulate cell responses and may lead to the impairment or even failure of tissue function as a result of mechanotransduction... -
Federal
Woman skeletal muscle transcriptome with bed rest and countermeasures.
National Aeronautics and Space Administration —
Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading... -
Federal
Gene responses in mouse brain to long-term exposure to microgravity
National Aeronautics and Space Administration —
The spaceflight experiment was carried out using male C57BL/10J mice (8 weeks old at launch). Wild type mice (n=3) were launched by Space Shuttle Discovery and housed... -
Federal
Gene responses in mouse brain to long-term exposure to microgravity
National Aeronautics and Space Administration —
The spaceflight experiment was carried out using male C57BL/10J mice (8 weeks old at launch). Wild type mice (n=3) were launched by Space Shuttle Discovery and housed... -
Federal
Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment
National Aeronautics and Space Administration —
We address a key baseline question of whether gene expression changes are induced by the orbital environment and then we ask whether undifferentiated cells cells... -
Federal
MESSAGE 2 space experiment with Rhodospirillum rubrum S1H
National Aeronautics and Space Administration —
R. rubrum S1H inoculated on solid agar rich media was sent to the ISS in October 2003 (MESSAGE-part 2 experiment). After 10 days flight R. rubrum cultures returned... -
Federal
T Cell Activation in Microgravity Compared to 1g (Earth s) Gravity
National Aeronautics and Space Administration —
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (mg). Immunosuppression during... -
Federal
BASE-A space experiment with Rhodospirillum rubrum S1H
National Aeronautics and Space Administration —
R. rubrum S1H inoculated on solid minimal media was sent to the ISS in September 2006 (BASE-A experiment). After 10 days flight R. rubrum cultures returned back to... -
Federal
Salmonella Typhimurium transcription profiles in space flight
National Aeronautics and Space Administration —
Salmonella transcription profiles were obtained from samples flown on space shuttle mission STS-115 and compared to profiles from Salmonella grown under identical... -
Federal
Root transcriptome remodeling of Arabidopsis in response to high levels of magnesium sulfate
National Aeronautics and Space Administration —
Martian regolith (unconsolidated surface material) is a potential medium for plant growth in bioregenerative life support systems during manned missions on Mars.... -
Federal
Radiation responses in peripheral white blood cells of smokers and non-smokers
National Aeronautics and Space Administration —
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not... -
Federal
An environment with strong gravitational and magnetic field alterations synergizes to promote variations in Arabidopsis thaliana callus global transcriptional state
National Aeronautics and Space Administration —
Using diamagnetic levitation we have exposed A. thaliana in vitro callus cultures to five environments with different levels of effective gravity (from levitation...