Water-quality constituents were measured along planned survey lines, which were generally perpendicular to the shoreline and spaced 100 meters apart, over an approximately 2.3-mile section of nearshore Lake Erie on June 10-12, 2019 (survey 1), and August 19-21, 2019 (survey 2), with a YSI EcoMapper autonomous underwater vehicle (AUV) using an undulating dive pattern (a 15-degree dive angle between the surface and 6 feet above the bottom). Water-quality data collected in this area included three-dimensional measurements of water temperature, specific conductance, pH, dissolved oxygen, chlorophyll, and phycocyanin (blue-green algae). The water-quality data were measured at 1-second intervals and were geo-referenced with the AUV onboard Global Positioning System (GPS WAAS) system. There was a total of 40 survey lines which typically started about 50 meters offshore and ended 500 meters offshore, and the survey lines covered the area around the mouth of Euclid Creek, Villa Angela Beach, Wildwood Marina, and the Easterly Wastewater Treatment Plant. Data were post-processed with a custom MATLAB script. Each water-quality measurement has an associated latitude and longitude (WGS84) and sample depth (in meters) below the surface. All water-quality sensors were calibrated per USGS standard methods prior to the start of the survey. These water-quality measurements were collected over the course of six total days, three in early summer (survey 1) and three in late summer (survey 2), to characterize circulation, mixing, and transport patterns in nearshore Lake Erie in the vicinity of Euclid Creek and Villa Angela Beach.