This U.S. Geological Survey (USGS) Data Release provides continuously measured water-quality data collected from four Indian Creek sites in Johnson County, Kansas during July 22-25, 2014 and August 21-27, 2015. Water-quality monitors were used to measure water temperature, dissolved oxygen, pH, specific conductance, turbidity, chlorophyll, phycocyanin, and nitrate at fifteen-minute intervals. This data release was produced in compliance with the federal open-data requirements as a way to make scientific products associated with USGS research efforts and publications available to the public. This dataset includes all continuously-measured data collected at short-term fixed site locations as part of a study to describe the spatiotemporal variability of nutrients in Indian Creek.