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    • Transient gene expression profile changes of confluent human fibroblast cells in spaceflight

    Metadata Updated: December 7, 2023

    Microgravity or an altered gravity environment from the static 1g has been shown to influence global gene expression patterns and protein levels in cultured cells or animals but it is unclear how these changes in gene and protein expressions are related to each other or are related to other factors regulating such changes. Recent advancement in the field of molecular biology revealed that a different class of RNA the small non-coding microRNA (miRNA) can have a broad effect on gene expression networks by mainly inhibiting the translational process. In this experiment conducted on the International Space Station we propose to test the hypotheses that miRNA profiles will be altered in the space environment and that cellular responses to DNA damage in space are different from those on the ground.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: us-pd

    Downloads & Resources

    Dates

    Metadata Created Date January 31, 2023
    Metadata Updated Date December 7, 2023
    Data Update Frequency irregular

    Metadata Source

    Harvested from NASA Data.json

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date January 31, 2023
    Metadata Updated Date December 7, 2023
    Publisher National Aeronautics and Space Administration
    Maintainer
    Identifier nasa_genelab_GLDS-118_v5nq-hfkp
    Data First Published 2021-05-21
    Data Last Modified 2023-01-26
    Category Earth Science
    Public Access Level public
    Data Update Frequency irregular
    Bureau Code 026:00
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Metadata Catalog ID https://data.nasa.gov/data.json
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id d3b13a3d-cc3e-41ea-a6c3-6b63ff2b18e8
    Harvest Source Id 58f92550-7a01-4f00-b1b2-8dc953bd598f
    Harvest Source Title NASA Data.json
    Homepage URL https://data.nasa.gov/d/v5nq-hfkp
    License http://www.usa.gov/publicdomain/label/1.0/
    Program Code 026:005
    Source Datajson Identifier True
    Source Hash 2e2cd8dd665248edcf9af2d2e396621fb0ad73f011ac76eb259ac91d04e37ba3
    Source Schema Version 1.1

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