Standard Reference Material (SRM) 968 and its reissues are human serum based materials used as validation standards by clinical, epidemiological, and nutrition laboratories. Historically, about 300 units of this SRM have been sold annually. Based on this annual sales projection, as of November 1, 2015 there were about 16 months of inventory of the current issue: SRM 968e Fat-Soluble Vitamins, Carotenoids, and Cholesterol in Human Serum. To avoid a gap in service to our customers, it is necessary to have the next issue of SRM 968 available for use in several NIST-organized interlaboratory comparison studies. Candidate SRM 968f Fat-Soluble Vitamins in Human Serum was prepared by the contractor as a two-component renewal. Approximately 3000 (± 10 %) vials of each of the two serum pools were delivered to NIST in March 2016. This material will be certified by NIST for retinol, alpha- and beta-/gamma-tocopherol. Other selected analytes measured by collaborating laboratories will be provided as reference or information values. Samples for these studies were shipped to participants in the NIST Micronutrients Measurement Quality Assurance Program for analysis beginning in early June 2016. NIST will evaluate this data for possible value assignment of the analytes of interest.