Broadly, recovery of threatened and endangered species requires specific management actions by natural resource managers at a fine scale. We used a systematic conservation planning framework to outline conservation goals across multiple land-uses, including native habitat protection and identifying endangered species-specific recovery areas while minimizing intrusion on existing hunting areas on the island of Lanai. We used spatial prioritization tools to generate multiple scenarios where both conservation and hunting areas (deemed zones for analysis purposes) were delineated to meet land-use goals. These delineated areas will help land managers to minimize conflicts between uses for populations of non-native game animals and the conservation and restoration of native plant species in climate resilient areas. This dataset includes one data table (.csv): a list of the plant species included in the analysis, and their listed federal status.