High resolution bathymetric, sea-floor backscatter, and seismic-reflection data were collected offshore of southeastern Louisiana aboard the research vessel Point Sur on May 19-26, 2017, in an effort to characterize mudflow hazards on the Mississippi River Delta front. As the initial field program of a research cooperative between the U.S. Geological Survey, the Bureau of Ocean Energy Management, and other Federal and academic partners, the primary objective of this cruise was to assess the suitability of sea-floor mapping and shallow subsurface imaging tools in the challenging environmental conditions found across delta fronts (for example, variably distributed water column stratification and widespread biogenic gas in the shallow subsurface). Approximately 675 kilometers (km) of multibeam bathymetry and backscatter data, 420 km of towed chirp data, and 550 km of multichannel seismic data were collected. Varied mudflow (gully, lobe), prodelta morphologies, and structural features were imaged in selected survey areas from Pass a Loutre to Southwest Pass.