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Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus

Metadata Updated: June 5, 2025

An experimental challenge of Influenza A virus in genetically modified TMPRSS2 knockout pigs. Resources in this dataset:

Resource Title: Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus File Name: TMPRSS2 dataset.xlsx Resource Description: Supporting data for: Nasal shedding of A/swine/Iowa/A02524480/2020 (IA/20) H1N1 by virus titration on cell culture or qRT-PCR; Infection of IA/20 H1N1 in WT and TMPRSS2-/- pigs; Immunohistochemical (IHC) staining of Influenza A virus nucleoprotein; Cytokine and chemokine panel performed on bronchioalveolar lavage fluid.

Access & Use Information

Public: This dataset is intended for public access and use. License: us-pd

Downloads & Resources

Dates

Metadata Created Date March 30, 2024
Metadata Updated Date June 5, 2025

Metadata Source

Harvested from USDA JSON

Additional Metadata

Resource Type Dataset
Metadata Created Date March 30, 2024
Metadata Updated Date June 5, 2025
Publisher Agricultural Research Service
Maintainer
Identifier 10.15482/USDA.ADC/1529793
Data Last Modified 2025-05-06
Public Access Level public
Bureau Code 005:18
Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
Schema Version https://project-open-data.cio.gov/v1.1/schema
Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
Harvest Object Id 72af86df-3f39-4895-8918-41a5888f7325
Harvest Source Id d3fafa34-0cb9-48f1-ab1d-5b5fdc783806
Harvest Source Title USDA JSON
License https://www.usa.gov/publicdomain/label/1.0/
Old Spatial {"type": "Point", "coordinates": -93.617248535156, 42.044002396934}
Program Code 005:040
Source Datajson Identifier True
Source Hash 581ddd7c6dbbc38807829013bc4aebb537a17e675a16c0629b99031c82d55979
Source Schema Version 1.1
Spatial {"type": "Point", "coordinates": -93.617248535156, 42.044002396934}
Temporal 2022-10-01/2023-05-31

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