The National Water Quality Network (NWQN) for Rivers and Streams includes 113 surface-water river and stream sites monitored by the U.S. Geological Survey (USGS) National Water Quality Program, National Water-Quality Assessment (NAWQA) Project. The NWQN includes 19 large river coastal sites, 44 large river inland sites, 30 wadeable stream reference sites, 10 wadeable stream urban sites, and 10 wadeable stream agricultural sites. In addition to the 113 NWQN sites, 3 large inland river monitoring sites from the USGS Cooperative Water Program are also included in this annual water-quality reporting Web site to be consistent with previous USGS studies of nutrient transport in the Mississippi-Atchafalaya River Basin. This data release provides streamflow, nutrient, pesticide and sediment data collected and analyzed by NWQN and other historical water-quality networks from 1963-2016. Data from this release are presented at the USGS Tracking Water Quality page: http://cida.usgs.gov/quality/rivers/home.