Seismic data were recorded from the R/V San Lorenzo (RVSL; receive vessel) of a two-vessel marine sparker seismic survey conducted by the U.S. Geological Survey (USGS) in April of 2021 off the coast of Santa Cruz, California (USGS field activity 2021-619-FA). The R/V Parke Snavely (RVPS; source vessel) towed a marine sparker sound source along seven depth site transects ranging between 25 and 600 meters. The RVSL maintained a nearly stationary position at the midpoint of each transect and recorded sound data with a broadband omnidirectional Cetacean Research CR3 hydrophone positioned between 10- and 20-meters water depth below the RVSL. RVSL receive seismic data are presented in SEG-Y format. Shot point navigation are provided in an accompanying comma-delimited text file, as well as in a shapefile for visualization purposes. Navigation data for the source and receiver vessels, as well as seismic data from the source vessel, sound velocity, and other survey data, are provided elsewhere in this data release.