This data release contains compiled groundwater-withdrawal data from 1980 to 2018 for the Hueco Bolson, Mesilla Basin, and the Rio Grande alluvium in El Paso and Hudspeth Counties, Texas. The Hueco Bolson and Mesilla Basin are major aquifers in Texas. The Hueco Bolson part of the aquifer is located east of the Franklin mountains, and the Mesilla Basin part of the aquifer is west of the Franklin mountains and extends west into New Mexico (George and others, 2019d). Most groundwater-withdrawal volumes were distributed to wells and separated into water-use categories. The data were compiled, distributed, and categorized as part of the U.S. Geological Survey's involvement in the Transboundary Aquifer Assessment Program. The Transboundary Aquifer Assessment Act was originally signed into law as Public Law 109-448 by the 109th United States Congress in 2006. This law directed the Secretary of Interior to establish a U.S.-Mexico Transboundary Aquifer Assessment Program (TAAP) to systematically assess priority aquifers along the U.S.-Mexico international boundary. The priority aquifers that were specified include the Hueco Bolson and Mesilla Basin in Texas and New Mexico, and the Santa Cruz and San Pedro aquifers in Arizona. The Rio Grande alluvium overlies older basin fill material and is considered part of the Mesilla Basin alluvial aquifer (Ryder, 1996). The TAAP was established in 2009 after binational negotiations led to the signing of the "Joint Report of the Principal Engineers Regarding the Joint Cooperative Process United States-Mexico for the Transboundary Aquifer Assessment Program" (International Boundary and Water Commission, 2009; U.S. Geological Survey, 2019). TAAP research in the United States is a collaborative effort between the U.S. Geological Survey, Arizona Water Resources Research Center, New Mexico Water Resources Research Institute, and the Texas Water Resources Institute (U.S. Geological Survey, 2019).