This report summarizes estimates of “natural” and “unimpaired” flows for all areas in the Central Valley tributary to the Sacramento – San Joaquin Delta (Delta) for the period spanning water years 1922-2014. A major objective of this report is to clarify the conceptual differences between natural and unimpaired flows. In spite of the Department’s previous attempts to distinguish between natural conditions and its calculation of theoretical unimpaired flows, unimpaired flow estimates have frequently been used as a surrogate measure of natural conditions, presumably because natural flow estimates were unavailable. This report contains the Department’s first published estimates of natural flows; these estimates are derived from complex simulation models and are based on published estimates of natural vegetation cover and associated evapotranspiration.