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Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Catalog Last Checked: April 21, 2026 at 08:05 PM | Dataset Last Updated: April 06, 2022
Dataset for 'Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells' by Sheau-Fung Thai et al., accepted by Materials Express. For the data set: DEG: differentially expressed genes 33-MWCNT: parent MWCNT 55-OH-MWCNT: MWCNT modified with -OH group 66-COOH-MWCNT: MWCNT modified with -COOH group. MWCNT_66_30 means cells treated with 66-COOH-MWCNT at 30 microgram/ml. This dataset is associated with the following publication: Thai, S., C. Jones, B. Robinette, H. Ren, B. Vallanat, A. Astriab Fisher, and K. Kitchin. Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells. Materials Express. American Scientific Publishers, VALENCIA, CA, USA, 14(3): 403-415, (2024).

Resources

9 resources available

  • MWCNT 33_1.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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  • MWCNT 33_10.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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  • MWCNT 33_3.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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  • MWCNT 55_10-1.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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  • MWCNT 55_10.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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  • MWCNT 55_30-1.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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  • MWCNT 55_30.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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  • MWCNT 66_10.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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  • MWCNT 66_30.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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Complete Metadata
@type dcat:Dataset
accessLevel public
bureauCode 
[
  "020:00"
]
contactPoint 
{
  "fn": "Sheau-Fung Thai",
  "hasEmail": "mailto:thai.sheau-fung@epa.gov"
}
description Dataset for 'Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells' by Sheau-Fung Thai et al., accepted by Materials Express. For the data set: DEG: differentially expressed genes 33-MWCNT: parent MWCNT 55-OH-MWCNT: MWCNT modified with -OH group 66-COOH-MWCNT: MWCNT modified with -COOH group. MWCNT_66_30 means cells treated with 66-COOH-MWCNT at 30 microgram/ml. This dataset is associated with the following publication: Thai, S., C. Jones, B. Robinette, H. Ren, B. Vallanat, A. Astriab Fisher, and K. Kitchin. Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells. Materials Express. American Scientific Publishers, VALENCIA, CA, USA, 14(3): 403-415, (2024).
distribution 
[
  {
    "title": "MWCNT 33_1.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2033_1.xlsx"
  },
  {
    "title": "MWCNT 33_10.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2033_10.xlsx"
  },
  {
    "title": "MWCNT 33_3.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2033_3.xlsx"
  },
  {
    "title": "MWCNT 55_10-1.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2055_10-1.xlsx"
  },
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    "title": "MWCNT 55_10.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2055_10.xlsx"
  },
  {
    "title": "MWCNT 55_30-1.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2055_30-1.xlsx"
  },
  {
    "title": "MWCNT 55_30.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2055_30.xlsx"
  },
  {
    "title": "MWCNT 66_10.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529906/MWCNT%2066_10.xlsx"
  },
  {
    "title": "MWCNT 66_30.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
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]
identifier https://doi.org/10.23719/1529906
keyword 
[
  "HepG2 cells",
  "Multi-wall carbon nanotubes",
  "Target Filter Analysis",
  "acute phase response signaling",
  "cholesterol biosynthesis pathways",
  "microrna",
  "oxidative stress",
  "signaling pathways",
  "transcriptomics"
]
license https://pasteur.epa.gov/license/sciencehub-license.html
modified 2022-04-06
programCode 
[
  "020:000"
]
publisher 
{
  "name": "U.S. EPA Office of Research and Development (ORD)",
  "subOrganizationOf": {
    "name": "U.S. Environmental Protection Agency",
    "subOrganizationOf": {
      "name": "U.S. Government"
    }
  }
}
references 
[
  "https://doi.org/10.1166/mex.2024.2641"
]
rights 
null
title Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells

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