Dataset for journal article 'Determinants of gene expression in the human liver: Impact of aging and sex on xenobiotic metabolism'
Gene array data files compared gene expression profiles in liver samples from young (21-45 years) and old (69+ years) men and women to determine changes in the expression of xenobiotic metabolism enzymes and transporters. We identified genes that were differentially expressed in males only, females only, or in all individuals between the young and old using microarray.
This dataset is associated with the following publication:
Corton, J., J. Lee, J. Liu, H. Ren, B. Vallanat, and M. Devito. Determinants of Gene Expression in the Human Liver: Impact of Aging and Sex on Xenobiotic Metabolism. Experimental Gerontology. Elsevier Science Ltd, New York, NY, USA, 169: 111976, (2022).
Resources
1 resource available
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE133815
FILE
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Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Jon Corton",
"hasEmail": "mailto:corton.chris@epa.gov"
}
|
| description | Gene array data files compared gene expression profiles in liver samples from young (21-45 years) and old (69+ years) men and women to determine changes in the expression of xenobiotic metabolism enzymes and transporters. We identified genes that were differentially expressed in males only, females only, or in all individuals between the young and old using microarray. This dataset is associated with the following publication: Corton, J., J. Lee, J. Liu, H. Ren, B. Vallanat, and M. Devito. Determinants of Gene Expression in the Human Liver: Impact of Aging and Sex on Xenobiotic Metabolism. Experimental Gerontology. Elsevier Science Ltd, New York, NY, USA, 169: 111976, (2022). |
| distribution |
[
{
"title": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE133815",
"accessURL": "https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE133815"
}
]
|
| identifier | https://doi.org/10.23719/1528717 |
| keyword |
[
"P450 enzyme activities",
"Xenobiotic metabolizing genes",
"age",
"human liver",
"sex",
"transcript profiling"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-07-06 |
| programCode |
[
"020:000"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1016/j.exger.2022.111976"
]
|
| rights |
null
|
| title | Dataset for journal article 'Determinants of gene expression in the human liver: Impact of aging and sex on xenobiotic metabolism' |
