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    • Dataset for Extracellular Vesicles altered by Per- and Polyfluoroalkyl Substance Mixtures: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health.

    Metadata Updated: February 26, 2024

    These data represent underlying data generated for the study titled 'Extracellular Vesicles altered by Per- and Polyfluoroalkyl Substance Mixtures: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health'. Data include extracellular vesicle particle count and size distribution from nanoparticle tracking analysis; microRNA expression data from mRNA sequencing in extracellular vesicles; PFAS signature data from mass spectrometry analysis of isolated HepG2 cell lysates and their secreted extracellular vesicles; in vitro cell viability data.

    This dataset is associated with the following publication: Carberry, C., J. Bangma, L. Koval, D. Keshava, h. Hartwell, M. Sokolsky, R. Fry, and J. Rager. Extracellular vesicles altered by a per- and polyfluoroalkyl substance mixture: in vitro dose-dependent release, chemical content, and microRNA signatures involved in liver health. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 197(2): 155-169, (2024).

    Access & Use Information

    Public: This dataset is intended for public access and use. License: See this page for license information.

    Downloads & Resources

    References

    https://doi.org/10.1093/toxsci/kfad108
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10823775

    Dates

    Metadata Created Date February 26, 2024
    Metadata Updated Date February 26, 2024

    Metadata Source

    Harvested from EPA ScienceHub

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date February 26, 2024
    Metadata Updated Date February 26, 2024
    Publisher U.S. EPA Office of Research and Development (ORD)
    Maintainer
    Identifier https://doi.org/10.23719/1529913
    Data Last Modified 2023-02-16
    Public Access Level public
    Bureau Code 020:00
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Harvest Object Id 2eaa4d60-5fa4-4a4b-89f3-5136b52510c8
    Harvest Source Id 04b59eaf-ae53-4066-93db-80f2ed0df446
    Harvest Source Title EPA ScienceHub
    License https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html
    Program Code 020:000
    Publisher Hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
    Related Documents https://doi.org/10.1093/toxsci/kfad108, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10823775
    Source Datajson Identifier True
    Source Hash 5cad46531ed38328c07b3c5dbb0286b147a124fd3762a0c014af3f2f5f72e8c7
    Source Schema Version 1.1

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