Dataset for Extracellular Vesicles altered by Per- and Polyfluoroalkyl Substance Mixtures: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health.
These data represent underlying data generated for the study titled 'Extracellular Vesicles altered by Per- and Polyfluoroalkyl Substance Mixtures: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health'. Data include extracellular vesicle particle count and size distribution from nanoparticle tracking analysis; microRNA expression data from mRNA sequencing in extracellular vesicles; PFAS signature data from mass spectrometry analysis of isolated HepG2 cell lysates and their secreted extracellular vesicles; in vitro cell viability data.
This dataset is associated with the following publication:
Carberry, C., J. Bangma, L. Koval, D. Keshava, h. Hartwell, M. Sokolsky, R. Fry, and J. Rager. Extracellular vesicles altered by a per- and polyfluoroalkyl substance mixture: in vitro dose-dependent release, chemical content, and microRNA signatures involved in liver health. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 197(2): 155-169, (2024).
Resources
1 resource available
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PFASEVs_Tables.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Jacqueline Bangma", "hasEmail": "mailto:bangma.jacqueline@epa.gov" } |
| description | These data represent underlying data generated for the study titled 'Extracellular Vesicles altered by Per- and Polyfluoroalkyl Substance Mixtures: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health'. Data include extracellular vesicle particle count and size distribution from nanoparticle tracking analysis; microRNA expression data from mRNA sequencing in extracellular vesicles; PFAS signature data from mass spectrometry analysis of isolated HepG2 cell lysates and their secreted extracellular vesicles; in vitro cell viability data. This dataset is associated with the following publication: Carberry, C., J. Bangma, L. Koval, D. Keshava, h. Hartwell, M. Sokolsky, R. Fry, and J. Rager. Extracellular vesicles altered by a per- and polyfluoroalkyl substance mixture: in vitro dose-dependent release, chemical content, and microRNA signatures involved in liver health. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 197(2): 155-169, (2024). |
| distribution |
[ { "title": "PFASEVs_Tables.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1529913/PFASEVs_Tables.xlsx" } ] |
| identifier | https://doi.org/10.23719/1529913 |
| keyword |
[ "Mixtures", "PFAS", "extracellular vesicles", "liver toxicity" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html |
| modified | 2023-02-16 |
| programCode |
[ "020:000" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
[ "https://doi.org/10.1093/toxsci/kfad108", "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10823775" ] |
| rights |
null
|
| title | Dataset for Extracellular Vesicles altered by Per- and Polyfluoroalkyl Substance Mixtures: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health. |
