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Data from: Expansion of Proteome-wide <i>Coxiella burnetii </i>Comparative T-cell Epitope Prediction to Include Small Ruminant Hosts

Metadata Updated: April 21, 2025

T-cell epitopes represent sampled environmental- and self-peptides loaded into major histocompatibility complex (MHC) proteins. Bioinformatic tools have been produced to predict these interactions for many species, providing peptides of interest in vaccine development studies.Prior work by the researchers (DOI: 10.1186/s12859-021-04181-w) assessed the ability of Coxiella burnetii proteins to interact with MHC alleles in human, mouse, and cattle species, the data from which is available on the Open Science Framework repository with accession number RN6QA (DOI: 10.17605/OSF.IO/RN6QA).Presently, bioinformatic programs NetBoLAIIpan 1.0 and NetMHCpan 4.1 were employed to predict T-cell epitopes within the C. burnetii proteome for the small ruminant species and to expand cattle predictions. The new datasets available herein provide the species, amino acid sequence, position within the protein, GenBank ID, allele name, and the predicted binding strength for each tested peptide.

Access & Use Information

Public: This dataset is intended for public access and use. License: Creative Commons CCZero

Downloads & Resources

Dates

Metadata Created Date March 30, 2024
Metadata Updated Date April 21, 2025

Metadata Source

Harvested from USDA JSON

Additional Metadata

Resource Type Dataset
Metadata Created Date March 30, 2024
Metadata Updated Date April 21, 2025
Publisher Agricultural Research Service
Maintainer
Identifier 10.15482/USDA.ADC/24712827.v1
Data Last Modified 2024-07-09
Public Access Level public
Bureau Code 005:18
Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
Schema Version https://project-open-data.cio.gov/v1.1/schema
Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
Harvest Object Id da06fe8e-6ab2-46d5-9453-a52373a2a159
Harvest Source Id d3fafa34-0cb9-48f1-ab1d-5b5fdc783806
Harvest Source Title USDA JSON
License https://creativecommons.org/publicdomain/zero/1.0/
Program Code 005:040
Source Datajson Identifier True
Source Hash 5a28c4e9bfacf4c986c759c22b6b6aff6abd23a83ae9e08d12e9bd392539b06b
Source Schema Version 1.1
Temporal 2023-02-01/2023-02-01

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