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    • Data from: Antigenic distance between North American swine and human seasonal H3N2 influenza A viruses as an indication of zoonotic risk to humans

    Metadata Updated: June 5, 2025

    An investigation of antigenic relationships between North American swine H3N2 influenza A viruses (IAV) and human seasonal vaccine strains was conducted to assess the zoonotic risk to humans. Human seasonal H3N2 vaccine strains isolated from 1973 to 2014 (n=20) were obtained from the World Health Organization Global Influenza Surveillance and Response Network through St. Jude Children’s Research Hospital to use for serological assays, such as hemagglutination inhibition (HI) assays. Human seasonal vaccine strains were cultured on MDCK cells or eggs and the HA gene was verified by sequencing on a Sanger method at National Animal Disease Center (NADC). A consensus HA sequence was generated using Geneious Software. Resources in this dataset:Resource Title: Consensus sequences of hemagglutinin (HA) gene segments. File Name: Vincent_H3N2 HuVac strains.rtfResource Description: The data set includes sequences of hemagglutinin (HA) gene of human seasonal influenza A vaccine strains used in hemagglutination inhibition (HI) assays as references to assess the zoonotic risk of North American swine H3N2 strains to humans. The text file lists the consensus sequence of HA gene segment from each human H3N2 influenza A vaccine strain.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: us-pd

    Downloads & Resources

    Dates

    Metadata Created Date March 30, 2024
    Metadata Updated Date June 5, 2025

    Metadata Source

    Harvested from USDA JSON

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date March 30, 2024
    Metadata Updated Date June 5, 2025
    Publisher Agricultural Research Service
    Maintainer
    Identifier 10.15482/USDA.ADC/1522389
    Data Last Modified 2025-05-06
    Public Access Level public
    Bureau Code 005:18
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id 7ea3c6d0-b108-4f7c-861e-e35565d2fcfa
    Harvest Source Id d3fafa34-0cb9-48f1-ab1d-5b5fdc783806
    Harvest Source Title USDA JSON
    License https://www.usa.gov/publicdomain/label/1.0/
    Old Spatial {"type": "Polygon", "coordinates": -165.76171875, 25.572175556682, -165.76171875, 71.995974056837, -51.85546875, 71.995974056837, -51.85546875, 25.572175556682, -165.76171875, 25.572175556682}
    Program Code 005:040
    Source Datajson Identifier True
    Source Hash a335a050867cf03104ad3eea56db7e73a4ebe81b9f098cc12c5505be809b3589
    Source Schema Version 1.1
    Spatial {"type": "Polygon", "coordinates": -165.76171875, 25.572175556682, -165.76171875, 71.995974056837, -51.85546875, 71.995974056837, -51.85546875, 25.572175556682, -165.76171875, 25.572175556682}
    Temporal 1973-01-01/2014-12-31

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