This data release contains the analytical results and the evaluated source data files of a geospatial analysis for identifying areas in Alaska that may have potential for sediment-hosted Pb-Zn (lead-zinc) deposits. The spatial analysis is based on queries of statewide source datasets Alaska Geochemical Database (AGDB3), Alaska Resource Data File (ARDF), and Alaska Geologic Map (SIM3340) within areas defined by 12-digit HUCs (subwatersheds) from the National Watershed Boundary dataset. The packages of files available for download are: 1. "SedPbZn_Results_gdb.zip". The analytical results (.gbd - geodatabase format) for sediment-hosted Pb-Zn deposits are in a polygon feature class which contains the points scored for each source data layer query, the accumulative score, and a designation for high, medium, or low potential and high, medium, or low certainty for sediment-hosted Pb-Zn deposits for each HUC. An mxd file, layer file, and cartographic feature classes are provided for display of the results in ArcMap. 2. "SedPbZn_Results_kmz.zip". The analytical results (.kmz - keyhole markup language format) for sediment-hosted Pb-Zn deposits are shown as polygons containing the points scored for each source data layer query, the accumulative score, and designation of high, medium, or low potential and high, medium, or low certainty for sediment-hosted Pb-Zn deposits for each HUC. This file may be viewed in an Earth viewer, such as Google Earth. 3. "SedPbZn_Results_shape.zip". The analytical results (.shp - Esri shapefile format) for sediment-hosted Pb-Zn deposits are in a polygon feature class which contains the points scored for each source data layer query, the accumulative score, and designation for high, medium, or low potential and high, medium, or low certainty for sediment-hosted Pb-Zn deposits for each HUC. The results are also provided as a CSV file. 4. "SedPbZn_SourceData_gdb.zip". Source data (.gbd - geodatabase format); layers include AGDB3, ARDF, lithology from SIM3340, and HUC subwatersheds. An mxd file and cartographic feature classes are provided for display of the source data in ArcMap. Also included are two python scripts 1) to score the ARDF records based on the presence of certain keywords, and 2) to evaluate the ARDF, AGDB3, and lithology layers for the potential for sediment-hosted Pb-Zn deposits within subwatershed polygons. Users may modify the scripts to design their own analyses. 5. "SedPbZn_SourceData_shape.zip". Source data (.shp - Esri shapefile and .csv tabular formats); layers include ARDF and lithology from SIM3340, and HUC subwatersheds. The ARDF keyword tables available in the geodatabase package are presented here as CSV files. 6. "SedPbZn_Appendices.zip". Appendices 2-4 (.csv and .xlsx tabular formats) of the associated USGS Open File Report: OFR 2020-1147; https://doi.org/10.3133/ofr20201147